Gökmen Kahiloğulları

Monthly Archives: Haziran 2014

“CNS Spotlight: 2014 Fall Congress Quarterly Released”

The Congress Quarterly (cnsq) is the official newsmagazine of the CNS and is designed to reflect the changing nature of neurosurgery and foster discussion about the core being of the neurosurgeon, which is that of leadership, Read more

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Posted in: Genel

“Alzheimer’s disease: The role for neurosurgery – SNI 2014 “

Alzheimer’s disease: The role for neurosurgery

Julio Leonardo Barbosa Pereira1, Angela Downes1, Alessandra Gorgulho2, Vishal Patel1, Dennis Malkasian1, Antonio De Salles2
1 Department of Neurosurgery, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA, Read more

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Posted in: Genel

“Multidose Stereotactic Radiosurgery (9 Gy × 3) of the Postoperative Resection Cavity for Treatment”

Purpose: To evaluate the clinical outcomes with linear accelerator-based multidose stereotactic radiosurgery (SRS) to large postoperative resection cavities in patients with large brain metastases.Methods and Materials: Read more

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Posted in: Genel

Microsurgery for cerebral arteriovenous malformations: postoperative outcomes and predictors of complications in 264 cases

The authors conducted a study to assess the safety and efficacy of microsurgical resection of arteriovenous malformations (AVMs) and determine predictors of complications.

Methods. A total of 264 patients with cerebral AVMs were treated with microsurgical resection between 1994 and 2010 at the Jefferson Hospital for Neuroscience. A review of patient data was performed, including initial hemorrhage, clinical presentation, Spetzler-Martin (SM) grade, treatment modalities, clinical outcomes, and obliteration rates. Univariate and multivariate analyses were used to determine predictors of operative complications.

Results. Of the 264 patients treated with microsurgery, 120 (45%) patients initially presented with hemorrhage. There were 27 SM Grade I lesions (10.2%), 101 Grade II lesions (38.3%), 96 Grade III lesions (36.4%), 31 Grade IV lesions (11.7%), and 9 Grade V lesions (3.4%). Among these patients, 102 (38.6%) had undergone prior endovascular embolization. In all patients, resection resulted in complete obliteration of the AVM. Complications occurred in 19 (7.2%) patients and resulted in permanent neurological deficits in 5 (1.9%). In multivariate analysis, predictors of complications were increasing AVM size (OR 3.2, 95% CI 1.5–6.6; p = 0.001), increasing number of embolizations (OR 1.6, 95% CI 1.1–2.2; p = 0.01), and unruptured AVMs (OR 2.7, 95% CI 1–7.2; p = 0.05).

Conclusions. Microsurgical resection of AVMs is highly efficient and can be undertaken with low rates of morbidity at high-volume neurovascular centers. Unruptured and larger AVMs were associated with higher complication rates.

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Posted in: Genel